What is the treatment of choice for cutaneous anthrax?

The treatment of choice for cutaneous anthrax is ciprofloxacin. This antibiotic is a fluoroquinolone that is effective against Bacillus anthracis, the bacterium responsible for anthrax. Ciprofloxacin is particularly important due to its broad spectrum of activity and its efficacy against both naturally occurring and bioterrorism-related strains of anthrax.

While doxycycline is also an effective treatment for anthrax and is used in certain cases, ciprofloxacin is preferred in many treatment guidelines for its pharmacokinetic properties and established effectiveness.

Amoxicillin and penicillin can be used for treating anthrax as well; however, they are less favored in cases of cutaneous anthrax due to the potential for resistance and the need for better coverage against the spores of Bacillus anthracis. Ciprofloxacin provides a robust alternative, thus making it the first-line choice in clinical practice for this infection.