What is the first line treatment for Dengue Virus (DENV)?

The first line treatment for Dengue Virus (DENV) is supportive care and fluid replacement. Dengue is a viral infection transmitted by mosquitoes, and its management primarily focuses on alleviating symptoms and preventing complications rather than using specific antiviral therapies.

In cases of Dengue fever, patients often experience high fever, severe headache, pain behind the eyes, joint and muscle pain, and rash. The key objective in treatment is to maintain hydration and manage fever and pain, typically with acetaminophen. Adequate fluid replacement is crucial, especially in more severe cases such as Dengue hemorrhagic fever or Dengue shock syndrome, where fluid loss can lead to dehydration and shock.

The use of antibiotics is not appropriate because Dengue is caused by a virus, making antibiotics ineffective against the infection. Similarly, antiviral medications are not indicated since there are no specific antiviral agents approved for the treatment of Dengue. Corticosteroids have not proven to be beneficial in treating Dengue and can potentially lead to adverse effects, so their use is generally not recommended in this context.

Thus, supportive care and fluid replacement remain the cornerstone of treatment for Dengue Virus infection, ensuring that patients recover effectively while monitoring for any signs of severe disease.