What is the first line treatment for localized impetigo?

Topical mupirocin is the first-line treatment for localized impetigo due to its effectiveness against the common bacteria associated with the infection, primarily Staphylococcus aureus and Streptococcus pyogenes. Mupirocin is a topical antibiotic that is applied directly to the affected skin area, allowing for targeted treatment while minimizing systemic effects and potential side effects that can occur with oral antibiotics.

Localized impetigo often presents as superficial lesions that can be effectively managed with topical therapy. Mupirocin works by inhibiting bacterial protein synthesis, thus halting the growth of the bacteria causing the infection. Its local application is preferred especially in cases where the infection is not widespread, as it allows for a more direct and often quicker resolution of the infection.

Other options like oral antibiotics may be appropriate in cases of extensive impetigo, but for localized infections, mupirocin is the most efficient and least invasive method. Similarly, ciprofloxacin is not appropriate for first-line treatment of impetigo as it is not primarily effective against the common pathogens responsible for this condition. Cool compresses can provide symptomatic relief and help with crusting but do not treat the underlying bacterial infection.