How is the treatment of HSV Encephalitis primarily administered?

The primary treatment for HSV (Herpes Simplex Virus) encephalitis is administered intravenously. This method is essential because encephalitis affects the brain, which requires high concentrations of the antiviral medication, typically acyclovir, to penetrate the central nervous system effectively. Intravenous administration allows for rapid delivery and higher systemic levels of the medication, crucial in treating the potentially severe and acute nature of HSV encephalitis.

Other routes of administration, such as orally or subcutaneously, are not suitable for treating this serious condition due to the need for immediate and potent antiviral action that may not be achieved through those methods. Topical treatments are also inappropriate since encephalitis is an internal infection rather than one that could be treated through surface application. Thus, the intravenous route is essential for effectively managing the infection and improving patient outcomes.